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Rylaze (crisantaspase recombinant) is indicated as a component of a multi-agent chemotherapeutic regimen for the treatment of acute lymphoblastic leukemia (ALL) and lymphoblastic lymphoma (LBL) in adult and pediatric patients 1 year or older who have developed hypersensitivity to E. coli-derived asparaginase.

VYXEOS (daunorubicin and cytarabine liposome for injection) is indicated for treatment of adults with newly diagnosed therapy-related acute myeloid leukemia (t-AML) or AML with myelodysplasia-related changes (AML-MRC).

DEFITELIO (defibrotide sodium) solution for intravenous infusion is indicated for the treatment of adult and pediatric patients with severe hepatic veno-occlusive disease (VOD), also known as sinusoidal obstruction syndrome (SOS), following haematopoietic stem-cell transplantation (HSCT).

Consult the respective product monographs for contraindications, serious warnings and precautions, adverse reactions, interactions, dosing, and conditions of clinical use: here for Rylaze, here for VYXEOS and here for DEFITELIO. The Product Monographs are also available by calling 1-800-520-5568.

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CA-VYX-2400061E | September 2024

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